This episode begins with a flashback to Bristol 1665. In an underground tunnel some religious men travel with torches until the run into what looks like a group of people living underground. A man opens a scroll and says, "Demons, blood suckers, incubi, spreaders of the great great pestilence, you have been tried in front of God and this country and found guilty of witchcraft, heresy, satanic ritual, collusion with Beelzebub and of bringing disease and pestilence to the land. You are to be destroyed so that our kingdom might be cleansed of your devilry and the plague will be washed from or soil and taken from the air. Is there an order? Should we start with the infants? Your teeth will be smashed from your skull, and your head will be removed from your body."
In present day a woman is jogging in the park, and she stops when she comes across a shoe. On the grass their are signs that someone has been dragged in their own blood and she follows the trail until she sees a young man and a young woman lying in the mud covered in blood. At the hospital Lucy and the orderlies are rushing one of the victims down the hall, as Mitchell is mopping the floor. The police later announce that there has been a brutal attack on a young couple leaving one of them dead.
Mitchell walks into the room to the hospital room to see that the young man is unconscious and hooked up to a ventilator. He imagines unhooking him when Lucy walks in and asks what he is doing. He covers by claiming to be praying. Lucy says, I suppose the bad conditions in the hospital has lead you to believe in a monethestic deity. She tells him that the victim was a student and that this is murder inquiry because no one asks to have this done to them. She gets paged and says that she has to go because an anal abscess burst in geriatrics. Before she leaves, Lucy asks what happened to her drink and Mitchell tells her that he is busy tonight.
Back at the house, Annie brings George a cup of tea and opens the blinds. When he takes a sip he spits it back into the cup and asks what the hell is this. She tells him that there is no coffee, tea or milk in the house but that there is a shower. When George asks why no one has gone shopping Annie responds, "I don't know if you've noticed, but I've been struggling with the whole ghost thing the last couple of days. Strangely, being invisible, makes purchasing pyramid tea bags a touch awkward." When George asks where Mitchell is, because apparently, it's his turn Annie answers, "He hasn't so much as purchased a pint of milk in weeks. I can't remember the last time he washed up and as for cleaning the bathroom George, I don't think he's ever cleaned the bathroom." George tells her that he will handle it and Annie asks him if he wants to talk about Nina dumping him. George says that all he needs is tea. Annie tells him that he is depressed and that he needs to let out his emotions but George tells her that she has no idea what she is talking about.
They hear a knock on the door and when Annie looks out the window he sees Hugh. George goes downstairs and tells Hugh that Annie is gone and that she left a note saying that she is never coming back. He tells Hugh that Annie said that it was not his fault. Hugh says that this is exactly what happened with his ex girlfriend Kirsty. Hugh asks, "what's happening with me George? Why does every woman I love run a mile when I get just a little bit serious?"
Mitchell is underground at what looks like a tube station and sees Cara the woman that used to work at the hospital cafeteria. He asks what happened and where everyone is, and she responds that she is an orphan now that his pet, meaning George killed Herrick. Mitchell tells her that the two people were attacked by the waterside and that the killing has to stop because they cannot cover it up right now because there is no process anymore. When Cara says, "so," Mitchel responds, "so they'll find out about us. They'll come after us." When Cara says that she thinks that she would like that, Mitchell tells her to round everyone up at the old church.
Back at the house, George is sitting on the toilet when Annie barges in saying that she has been thinking about what happened to Hugh and has decided to get him back together with Kirsty. When George tells her that she cannot go interfering in peoples lives like that, Annie tells him that this is a regime change and that he is essential to her plan because he is another broken, rejected man. She tells him that he is the only one that can understand what he is going through. When George tells her that he is glad that his misery can be useful, Annie tells him that they are going to come from her, the men from the other side and that she has to be of some use and make the most of everyday that she has left. She tells him that after everything that happened with Saul that she feels cursed, or tainted somehow and George answers that he knows how she feels and so Annie proposes that he needs this too.
Mitchell meets Chief Constable William outside who greets him saying, "I see you're the new Herrick." Mitchell says that he is not the new Herrick and that he is not even standing in. He claims only to be a representative. Mitchell goes on to say that they have a situation and that he hopes that they can come to a similar agreement like the kind he had with Herrick. William responds, "I need to know that the people I'm deal with are reliable. Herrick was a despotic ginger ass but he had backbone and I don't see that in you." When Mitchell asks what he intends to do, William tells him that maybe it's time to start rounding up all of the vampires. Mitchell counters by reminding him that he is implicated already. Not one to be easily defeated William responds, "I'm chief constable. I'm on a first name terms with shitting home secretary and you're a bloody monster. Who the fuck is going to listen to you? No, if you want this deal work, you're going to have to come up with a lot more than you're implicated. You boys have access to money don't you?" Mitchell responds that they made some good investments in the 1800's and William tells him that not only is he going to need it, without coroner Quinn, that this is all academic and he walks away leaving Mitchell alone.